There’s nothing quite like digging into a bubbling-hot casserole packed with tender shrimp and melty cheese.
This baked shrimp casserole is a family favorite of mine—it’s quick to prep, irresistibly creamy, and perfect for any night when you want a cozy, hearty dish without fuss.
The contrast between juicy shrimp, gooey cheese, and crunchy golden topping makes this a comfort classic that always delivers.
Why I Love This Recipe
Ready in under 30 minutes
Shrimp stays juicy and flavorful
Buttery panko topping = instant texture boost
No soup cans or complicated steps
Crowd-pleasing for weeknights or gatherings
What You’ll Need (Ingredient Highlights)
Large shrimp – Cooked briefly to keep them plump and tender
Old Bay seasoning – Adds that signature coastal flavor
Mayonnaise – Gives the casserole creaminess without heaviness
Mozzarella + cheddar – A cheesy duo that melts like a dream
Garlic powder & pepper – Simple but bold flavor boosters
Panko bread crumbs – For the irresistible crunchy finish
Butter – Used for both greasing the dish and crisping the topping
Pro Tips Before You Start
Don’t overcook the shrimp—they’ll keep cooking in the oven
Use freshly shredded cheese for best meltability
Let the casserole rest before serving for easier scooping
Add a little lemon zest to brighten up the flavor
You can make ahead and bake right before serving
How to Make Baked Shrimp Casserole
Step 1: Preheat the Oven & Prep the Dish
Preheat your oven to 375°F (190°C).
Grease a 2½-quart casserole dish generously with butter and set it aside.
Step 2: Cook the Shrimp
Bring a large pot of water to a boil.
Add 1 tablespoon of salt and the Old Bay seasoning.
Drop in the shrimp and cook for about 30 seconds, just until they turn opaque.
Drain immediately and transfer to a mixing bowl.
Step 3: Mix the Casserole Base
Add mayonnaise, garlic powder, and black pepper to the shrimp.
Stir until everything is evenly coated.
Fold in the shredded mozzarella and cheddar cheese.
Transfer this creamy mixture to the prepared casserole dish, spreading evenly.
Step 4: Add the Crunchy Topping
In a small pan or microwave-safe bowl, melt the butter.
Stir in the panko bread crumbs until well coated.
Sprinkle the buttery crumbs evenly over the shrimp mixture.
Step 5: Bake & Broil
Bake uncovered for 13–15 minutes, or until the internal temperature reaches 145°F.
For a golden finish, broil the top for 1–2 minutes—keep a close eye!
Remove from the oven and let rest for 15 minutes before serving.
What to Serve It With
A crisp green salad with vinaigrette
Buttery garlic bread or crusty baguette
Lemon rice or herbed couscous
Roasted asparagus or broccoli
A chilled glass of white wine or sparkling water
Variations / Substitutions
Swap shrimp for scallops or cooked crab
Add a layer of sautéed spinach or mushrooms to the base
Use sour cream or Greek yogurt in place of part of the mayo
Try gouda or Monterey Jack instead of cheddar
Top with crushed Ritz crackers if you’re out of panko
Storage & Leftovers
Fridge: Store in an airtight container for up to 3 days
Reheat: Microwave in 30-second bursts or warm in a low oven
Freeze: Best enjoyed fresh, but you can freeze leftovers for up to 1 month
Make-ahead: Mix the base a day ahead, then top and bake when ready
Best texture tip: Broil briefly after reheating to re-crisp the topping
FAQs
Can I use pre-cooked shrimp?
Yes, but reduce baking time slightly to avoid overcooking.
What size shrimp works best?
Large shrimp (21–24 count) are ideal—they stay juicy and are easy to bite.
Is there a substitute for Old Bay?
You can use Cajun seasoning or a mix of paprika, celery salt, and pepper.
Can I make this dairy-free?
Use vegan cheese and mayo, and skip the butter (try olive oil instead).
Why let the casserole rest before serving?
It helps the cheeses set slightly, making it easier to scoop clean portions.
Can I double the recipe for a crowd?
Yes! Just bake in a larger dish and adjust time slightly as needed.
Is this good for meal prep?
Definitely—portion it out for easy lunches or dinner reheat.
Final Thoughts
This baked shrimp casserole hits every comfort-food note with minimal effort.
It’s one of those recipes that feels indulgent but takes hardly any time to prepare—just a quick boil, a creamy mix, and into the oven it goes.
The golden panko topping, the tender shrimp, the melted cheese—it all comes together like magic in a dish that’s cozy enough for a weeknight and impressive enough for guests.
Baked Shrimp Casserole
Ingredients
- 2 pounds large shrimp 21-24 count, peeled and deveined
- 1 tablespoon Old Bay seasoning plus 1 tablespoon salt for cooking water
- 2/3 cup mayonnaise
- 1/2 teaspoon garlic powder
- 1/2 teaspoon ground black pepper
- 1 tablespoon butter plus more to grease the pan
- 1/2 cup panko bread crumbs
- 4 ounces shredded mozzarella cheese
- 4 ounces shredded medium cheddar cheese
Instructions
- Preheat oven to 375°F. Grease a 2½-quart casserole dish with butter.
- In a large pot, bring water to a boil. Add salt and Old Bay, then shrimp.
- Cook 30 seconds until opaque. Drain.
- Mix shrimp with mayo, garlic powder, and pepper.
- Stir in mozzarella and cheddar.
- Transfer to casserole dish.
- Melt butter and combine with panko. Sprinkle over the top.
- See full steps with tips & photos → https://mischacrossing.com/baked-shrimp-casserole/
Notes
- You can substitute part of the shrimp with cooked crab or scallops for a seafood medley.
- Add a dash of hot sauce or cayenne to the mayo mixture for a little heat.
